I think that big problems in the world (like chronic homelessness, loneliness, depression, poverty, underrepresentation of groups, risks from A.I., global warming, etc.) are ridiculously complex - way more complex than the narratives about them suggest. The only approach I know of that I think has a meaningful shot to help solve such huge problems, which you might call “Scientific Entrepreneurship,” combines two methods into one: (1) Rigorous science to deeply understand the causal struct...